Oxford is a town in Worcester County, Massachusetts, United States. The population was 13,709 at the 2010 census.
According to the United States Census Bureau, the town has a total area of 27.5 square miles (71 km2), of which 26.6 square miles (69 km2) is land and 0.9 square miles (2.3 km2), or 3.20%, is water. The town sits in a valley, and much of its area lies in the flood plain of the French River, which runs through the town. A substantial parcel north and west of Oxford Center is held, for flood control purposes, by the U.S. Army Corps of Engineers. The land, known as Greenbriar, also serves as a nature preserve. It also serves to cut off east-west travel on former roads through the site. Route 20 runs east-west through North Oxford; running north-south Route 12, locally called Main Street; less than a mile of Route 56, connecting North Oxford with points north; and Interstate 395, linking Oxford to Worcester and eastern Connecticut with three local exits: Depot Road in North Oxford; Sutton Avenue, the main east-west street in Oxford Center; and Cudworth Road, on the Webster town line. The town used to include much of what is now Webster, on its southern border, but Oxford and neighboring Dudley both gave portions of their land to allow the creation of that town. Other towns bordering Oxford are Charlton on the west, Leicester and Auburn on the north, Millbury and Sutton on the east, and Douglas on the southeast.
As of the census of 2000, there were 13,352 people, 5,058 households, and 3,596 families residing in the town. The population density was 501.5 inhabitants per square mile (193.6 /km2). There were 5,228 housing units at an average density of 196.4 per square mile (75.8 /km2).